Poort combines in her research case-studies in the field of (bio-)technology with theoretical reflections on law-making processes. Poort analysed and redefined the concept of an interactive legislative approach which basic elements include communication on a horizontal level and responsiveness. Poort argues for an ethos of controversies: a normative way of legal thinking in which the controversies that characterize an issue are of central focus. By critically analyzing the role of experts, more specifically the role of ethics committees, and the boundaries of public participation in various case-studies in the field of technology, Poort operationalized the framework of controversies-thinking. Furthermore, Poort developed a concept of regulatory knowledge. Regulatory knowledge refers to the different types of knowledge that is required to come to adequate regulation for contemporary legal issues. Besides scientific knowledge (evidence-based), societal knowledge (see STS), adequate regulation also needs to consider legal knowledge, referring to legal values, knowledge about the legal system and legal culture. Currently, Poort is exploring whether sustainability involves an additional mode of knowledge. In this light, Poort analyzes the role that GM can play in establishing a sustainable food system, and how sustainability as such can and should be incorporated in the regulatory framework.